Endocrine Abstracts

Hirsutism, development of terminal body hair in women in unexpected areas, may result from different etiologies; 4.3% being nonclassical congenital adrenal hyperplasia (NCCAH) and acromegaly being one of the rarests. We here present a severe hirsutism case with acromegaly and NCCAH.Case: A 30-year-old woman with headache and visual field abnormalities was consultated by our clinic about her cranial imaging revealing a macroadenoma in pituitary localizati...

Aim: Sleep disturbances are widespread and closely associated with pituitary diseases, even those under long-term therapeutic management. The aim of this study was to investigate sleep quality, depression, anxiety, and physical activity in patients with non-functioning pituitary adenoma (NFPA) and determine the factors that might be associated with decreased quality of sleep.Method: Eighty-two patients with NFPAs and 82 age- and gender-matched control su...

Hyperthyroidism whether endogenous or exogenous in origin causes hemodynamic changes which associated with adverse cardiovascular outcomes. Ambulatory arterial Stiffness index (AASI) is a non invasive way of measuring arterial stiffness. Short term BP variability is derived from 24-hour ambulatory blood pressure monitoring (ABPM) recordings. BP variability and AASI are associtaed with increased cardiovascular risk.We aimed to investigate AASI and short t...

Purpose: The liver is known to be protected from steatosis under the influence of high GH/IGF-1. Cytokeratin 18 (CK18) and insulin-like growth factor binding protein 7 (IGFBP7) increase in liver steatosis and fibrosis. Whether decreasing lipid content completely protects the liver from metabolic alterations and the response of CK18 and IGFBP7 to liver changes in acromegaly is unknown.Methods: This single-center, multidisciplinary, cross-sectional study i...